Peace of Mind and astrology, the 4th house and planet or planets in it give you an indication on the same as the 4th house is a kind of happiness index, along with lords of 3rd ( subconscious /illusions )and the 5th house which represents Punya karma, Mind, and wisdom( Uttara Kalamrit), the 6th,8th, and 12th house represents mental duress of some kind ( Uttar Kalamrit).
Lets us try to understand this through an example.Consider Sagittarius ascendant, Saturn in 4th of 0 degrees, aspects the 6th,10th, and ascendant, Saturn is of separatist nature, the lesser dignity it represents the more malefic it is. Saturn is lord of 2nd and 3rd and it is the Significator of 6th,8th, and 12th, from 4th its aspect to 6th will enhance the qualities of 6th which include strife and mental agitation. The 5th house has the Moon, Rahu in it, the significator of the 5th, Jupiter is in the 8th and the lord of the 5th Mars is in the 9th under the impact of Rahu.
The native of Such placement normally does not find a stable peace of mind and may be opposed by all including close relatives, for whatever reasons there may be.
Note - The above analysis is Just an Indicator we cannot decide on an eventuality on the basis of a few planets and houses, we need to probe further and with diligence the impact and influences of the whole horoscope based on possibilities and probabilities it represents.
